Friday 30 October 2015

Almost All Psych Drug Use Is Unnecessary: Study

More than half a million people age 65 years or older die every year in the West from psychiatric drug use, and the worst part is that these death pills aren’t even effective at treating either mental illness or depression. 
Click here to see ...  
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Durjoy Majumder, Ph.D.
Assistant Professor
Department of Physiology
West Bengal State University

Vaccination: Have a look to the consequences in the world

A huge amount is still being invested in vaccination research. Have
a look what are consequences in the world.
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Durjoy Majumder, Ph.D.
Assistant Professor
Department of Physiology
West Bengal State University

Scientistic Fraud or Scientistic Religion

SCIENTISTIC FRAUD??? a new terminology!!! needed to know when we look for the precise meaning of “evolution,” “change,” “progress” and “Nature”? ...
1. "carbon dating is notoriously unreliable, with examples of testing on recent artifacts showing outrageous time stamps for items that are manifestly not ancient."
2. Why does the scientism crowd never admit they are subject to biases and greed (for grants)? How is it that science or the lab is magically averse to the failings of the rest of human endeavors?
3. empirical lab science and implicate lab bias into a ridiculous Marxist framework
Go link : Age of Transition 
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Durjoy Majumder, Ph.D.
Assistant Professor
Department of Physiology
West Bengal State University

Saturday 3 October 2015

Importance of AI in SB research

"Experimental data and public databases are not error-free and tend to be very noisy. Our language-based communication is one of fundamental limitations. Language inevitably reduces the world to words that represent some concepts or aspects of phenomena that the observer has recognized. This cognitive process inevitably involves inaccuracy. We are also inefficient in handling large volumes of data and information that are generated everyday. Vast data and knowledge is generated in biomedical domains without being properly processed, decoded and integrated as a consistent body of knowledge. In this regards, I consider scientific discovery in biomedical science still to be at the level of cottage industry, hence the need for industrial revolution in biomedical discovery. Recent progress in Artificial Intelligence (AI) has begun to address this issue, although we are a long way off from creating an engine of scientific discovery. My own experience in AI research leads me to believe that the day will come when AI will surpass human capability in biomedical research." 
                             - Hiroaki Kitano,The Systems Biology Institute, Tokyo, Japan Ref: Accelerating systems biology research and its real world deployment, Systems Biology & Applications, Sept. 2015, 1, Article number: 15009 (2015), doi:10.1038/npjsba.2015.9

Journals in Systems Biology


Following journals are devoted to publish articles in the area of Systems Biology:
  1. Biosystems
  2. BMC Systems Biology (open access)
  3. Frontiers in Systems Biology (open access)
  4. Gene Regulation and Systems Biology
  5. IET Systems Biology
  6. In Silico Biology (open access) 
  7. International Journal of Systems Biology (open access)  
  8. Journal of Biological Systems 
  9. Journal of Computational Systems Biology (open access)  
  10. Molecular BioSystems 
  11. Molecular Systems Biology (open access)  
  12. OMICS 
  13. Systems Biology and Applications  (open access)
  14. Systems Biology in Reproductive Medicine (open access)  
  15. Systems Biomedicine (open access)  
  16. WIREs Systems Biology and Medicine (only review articles, open access)  
  17. Annals of Systems Biology (open access)
  18. Avens Journal of Metabolomics & Systems Biology (open access)
Following journals publish articles in the area of Systems Biology with specific domain applications (Bio-informatics, Computational Biology or Omic science) :
  1. EURASIP Journal of Bioinformatics & Systems Biology (open access) 
  2. International Journal of Computer Intelligence in Bioinformatics and Systems Biology 
  3. Journal of Computer Science & Systems Biology (open access) 
  4. Journal of Metabolomics and Systems Biology
Following journals publish articles in the area of Systems Biology with Synthetic Biology application :
  1. InternationalJournal of Systems Biology & Biomedical Technologies 
  2. Journal of Molecular Engineering & Systems Biology (open access)  
  3. Systems and Synthetic Biology 
Journals from other domain also publish research articles in the area of Systems Biology : 
1. Analyst,
2. Computational and Mathematical Methods in Medicine (open access),
3. Journal of Systems Science & Complexity,
4. Interface (open access),
5. Nature Biotechnology,
6. PLoS ComputationalBiology (open access),
7. Theoretical Biology& Medical Modelling (open access)

Friday 2 October 2015

Virtual Environment in Mental Health Issues

See article : by Haniff D, Chamberlain A, Moody L and De Freitas S. (April 2014) Virtual Environment in Mental Health Issues: A review, Journal of Metabolomics and Systems Biology Vol 3, pp 1-10. 
DOI: 10.5897/JMSB11.003
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Ishita Chatterjee, Ph.D.
Dept. of Applied Psychology, University of Calcutta
Member, SSBTR

Individual's initiative in Big Data for Diseases

It's a great news that individuals are taking initiative to help in research, so more suitable environments are needed.
"For the Parkinson's disease (mPower) app, it took just three months to enroll 11,360 patients—the largest Parkinson's trial ever assembled."
See Nature Biotechnology (2015) 33: 885 doi: 10.1038/nbt.3341
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Durjoy Majumder, Ph.D.
Secretary, SSBTR

Saturday 22 August 2015

American Physiological Society

American Physiological Society makes call for paper on GI Systems Biology.
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Durjoy Majumder, Ph.D
Assistant Professor, Department of Physiology, West Bengal State University

Monday 17 August 2015

Importance of Behavioral Science in Health

There is gaining of importance of behavioural science in health care
management and this is very important to make better physician & responsible health care practitioners. see N Engl J Med April 5, 2012; 366:1265-1268, DOI: 10.1056/NEJMp1113274
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Ishita Chatterjee, Ph.D.
Dept. of Applied Psychology, University of Calcutta

Sunday 16 August 2015

Moral issues in Medicine

Money may influence science. It may be prominent, but when it is in subtle manner how it can be detected? Is there any mechanism to prevent it? Pharma industries are the major granting body for biomedical research. How students look for teacher? What is the direction of the biomedical science? See "Beyond Moral Outrage — Weighing the Trade-Offs of COI Regulation", N Engl J Med 2015; 372:2064-2068.  
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Durjoy Majumder, Ph.D.
Secretary, SSBTR



Friday 14 August 2015

Drug discovery (in silico-chemico-biology)

In the era of systems biology, drug discovery through computational approaches are gaining importance rather conventional approaches. See 
1. Curr Opin Biotech, 2011, 23:1-8 
2. Chem Bio Interact 2008, 171:165-176
3. Brief Bioinfo 2009, 10:579-591
4. Rev. Latinoamer. Quím. 2013, 41: 95-110,
5. Acta Pharmacologica Sinica (2012) 33: 1131–114,
6. Nature Reviews Drug Discovery 2, 321-327 (April 2003)|doi:10.1038/nrd1064.
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Sayan Mukherjee, M.Sc.

Ph.D. Student, University of Calcutta

Drug discovery in Systems Biology

PhD. thesis : Drug discovery in Systems Biology
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Sayan Mukherjee
Ph.D. Student, University of Calcutta

Drug information repository

Drug information repository in Briefings in Bioinformatics

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Sayan Mukherjee
Ph.D. Student, Calcutta University

Tuesday 4 August 2015

Pharmacometrics Markup Language (PharmML)

New direction in Pharmacology research using Systems Biology Markup Language. See Link
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Durjoy Majumder, Ph.D
Secretary, SSBTR

Working Together

People from across the disciplinary boundaries are working together in different sectors of the World for different health related issues, why not we? Please visit the link
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BISHWAJIT DAS
Member & Web Admin, SSBTR

Thursday 30 July 2015

Concern for India

Nature 14th May 2015, 521(7551): 125-252 made a special issue on Indian Science.
Durjoy Majumder, Ph.D.
Secretary, SSBTR

Skill-sets for Systems Biology Job

Have a look for the required skill-set as on Nature Jobs 2015 Aug. This is for Systems Biology job aspirants.
Durjoy Majumder, Ph.D.
Secretary, SSBTR

Saturday 18 July 2015

Link of other international societies

Different International Societies on Systems Science are focusing on
health care system
International Society for Systems Sciences & International Society for Knowledge and Systems Sciences

Important link that relate application of systems approach in relating health science with the behavioral science i.e., mind-body relationship in health care system: Saybrook University
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Ishita Chatterjee, Ph.D. 
Member, SSBTR
Dept. of Applied Psychology, University of Calcutta

Saturday 27 June 2015

Journal Impact Factor in Systems Biology

Systems Biology not only needs a multi-disciplinary frame-work but also needs a training to appreciate the multi-disiplinary culture. Majority of the science conferences do not have a strong review board and only publish abstracts, hence, academicians from Basic science background and General academia do not appreciate the importance of publications in conferences. Contrarily, engineering conferences publish full papers and they have a strong review board. However, science and general academicians, are not aware regarding the importance of engineering conferences. Please go through the article: Ideker T, Bafna V, and Lemberger T. Integrating scientific cultures, Mol Syst Biol 2007, 3:105, doi: 10.1038/msb4100145. This fact is more pronounced in India and may be the major hindrance in the development of   Systems Biology in India.

Sunday 7 June 2015

Systems Biology Markup Languages (SBML)

Systems Biology Markup Languages (SBML) is an universal format, based on XML and designed for community to reprsent, share and store the biological processes in a quantitative and relation centric manner. For details please visit: Nature Precedings or SBML project website.
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Durjoy Majumder, PhD
Secretary, SSBTR

Tuesday 5 May 2015

N-of-1 Project for Personalized Medicine

Recent time US President Barack Obama has announced a US$ 215 million project N-of-1 targeted to deliver Personalized Medicine (Nature 29 April 2015). Please see N-of-1 Project for Personalized Medicine & Precision Medicine Plan
The major suggestions of practicing methodologies actually coincides with the MORA (Middle-out Rationalist Approach) view.Please see Cross-roads, MORA and Multi-scaling
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Durjoy Majumder, PhD
Secretary, SSBTR